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1

Gene Expression Classification of Colon Cancer into Molecular Subtypes: Characterization, Validation, and Prognostic Value

Marisa, Laetitia, de Reyniès, Aurélien, Duval, Alex, Selves, Janick, Gaub, Marie Pierre, Vescovo, Laure, Etienne-Grimaldi, Marie-Christine, Schiappa, Renaud, Guenot, Dominique, Ayadi, Mira, Kirzin, Sy

Journal:

Year:

2013

Language:

english

File:

PDF, 1.17 MB

english, 2013

2

Candidate apoptotic and DNA repair gene approach confirms involvement of ERCC1, ERCC5, TP53 and MDM2 in radiation-induced toxicity in head and neck cancer

Borchiellini, D., Etienne-Grimaldi, M.C., Bensadoun, R.J., Benezery, K., Dassonville, O., Poissonnet, G., Llorca, L., Ebran, N., Formento, P., Château, Y., Thariat, J., Milano, G.

Journal:

Year:

2017

Language:

english

File:

PDF, 337 KB

english, 2017

3

Candidate mechanisms for capecitabine-related hand–foot syndrome

Gérard Milano, Marie-Christine Etienne-Grimaldi, Mireille Mari, Sandra Lassalle, Jean-Louis Formento, Mireille Francoual, Jean-Philippe Lacour, Paul Hofman

Journal:

British Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 935 KB

english, 2008

4

The mTOR-targeting drug temsirolimus enhances the growth-inhibiting effects of the cetuximab–bevacizumab–irradiation combination on head and neck cancer xenografts

Alexandre Bozec, Marie-Christine Etienne-Grimaldi, Jean-Louis Fischel, Anne Sudaka, Nicolas Toussan, Patricia Formento, Gérard Milano

Journal:

Year:

2011

Language:

english

File:

PDF, 297 KB

english, 2011

5

Selection of the Best Blood Compartment to Measure Cytidine Deaminase Activity to Stratify for Optimal Gemcitabine or Cytarabine Treatment

Peters, Godefridus J., Honeywell, Richard J., Maulandi, Marie, Giovannetti, Elisa, Losekoot, Nienke, Etienne-Grimaldi, Marie-Christine, Milano, Gerard, Serdjebi, Cindy, Ciccolini, Joseph

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2014

Language:

english

File:

PDF, 294 KB

english, 2014

6

Analysis of the dinucleotide repeat polymorphism in the epidermal growth factor receptor (EGFR) gene in head and neck cancer patients

Etienne-Grimaldi, M.-C.

Journal:

Annals of Oncology

Year:

2005

Language:

english

File:

PDF, 155 KB

english, 2005

7

Impact of erythropoietin on the effects of irradiation under hypoxia

Cristiana Lo Nigro, Monica Maffi, Jean Louis Fischel, Martino Monteverde, Paolo Catarsi, Federica Tonissi, Laura Lattanzio, Michela Riba, Marie-Christine Etienne-Grimaldi, Patricia Formento, Gerard Mi

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2009

Language:

english

File:

PDF, 487 KB

english, 2009

8

Prospective analysis of the impact of VEGF-A gene polymorphisms on the pharmacodynamics of bevacizumab-based therapy in metastatic breast cancer patients

Marie-Christine Etienne-Grimaldi, Patricia Formento, Armelle Degeorges, Jean-Yves Pierga, Rémi Delva, Xavier Pivot, Florence Dalenc, Marc Espié, Corinne Veyret, Jean-Louis Formento, Mireille Francoual

Journal:

British Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 847 KB

english, 2011

9

Multifactorial pharmacogenetic analysis in colorectal cancer patients receiving 5-fluorouracil-based therapy together with cetuximab–irinotecan

Marie-Christine Etienne-Grimaldi, Jaafar Bennouna, Jean-Louis Formento, Jean-Yves Douillard, Mireille Francoual, Isabelle Hennebelle, Etienne Chatelut, Eric Francois, Roger Faroux, Chaza El Hannani, J

Journal:

British Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.31 MB

english, 2012

10

Factors for Hematopoietic Toxicity of Carboplatin: Refining the Targeting of Carboplatin Systemic Exposure

Schmitt, A., Gladieff, L., Laffont, C. M., Evrard, A., Boyer, J.-C., Lansiaux, A., Bobin-Dubigeon, C., Etienne-Grimaldi, M.-C., Boisdron-Celle, M., Mousseau, M., Pinguet, F., Floquet, A., Billaud, E.

Journal:

Journal of Clinical Oncology

Year:

2010

Language:

english

File:

PDF, 1.29 MB

english, 2010

11

Dual HER 1-2 targeting of hormone-refractory prostate cancer by ZD1839 and trastuzumab

Patricia Formento, Jean-Michel Hannoun-Levi, Jean-Louis Fischel, Nicolas Magné, Marie-Christine Etienne-Grimaldi, Gérard Milano

Journal:

European Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 411 KB

english, 2004

12

Combination of bevacizumab and irradiation on uveal melanoma: an in vitro and in vivo preclinical study

Anne Sudaka, Antoine Susini, Cristiana Lo Nigro, Jean-Louis Fischel, Nicolas Toussan, Patricia Formento, Federica Tonissi, Laura Lattanzio, Elvio Russi, Marie-Christine Etienne-Grimaldi, Marco Merlano

Journal:

Investigational New Drugs

Year:

2013

Language:

english

File:

PDF, 230 KB

english, 2013

13

Cetuximab Pharmacokinetics in End-Stage Kidney Disease Under Hemodialysis

Thariat, J., Azzopardi, N., Peyrade, F., Launay-Vacher, V., Santini, J., Lecomte, T., Etienne-Grimaldi, M.-C., Paintaud, G., Milano, G.

Journal:

Journal of Clinical Oncology

Year:

2008

Language:

english

File:

PDF, 97 KB

english, 2008

14

Molecular patterns in deficient mismatch repair colorectal tumours: results from a French prospective multicentric biological and genetic study

Etienne-Grimaldi, M-C, Mahamat, A, Chazal, M, Laurent-Puig, P, Olschwang, S, Gaub, M-P, Formento, J-L, Formento, P, Sudaka, A, Boige, V, Abderrahim-Ferkoune, A, Benchimol, D, André, T, Houry, S, Fauch

Journal:

British Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 507 KB

english, 2014

15

New advances in DPYD genotype and risk of severe toxicity under capecitabine

Etienne-Grimaldi, Marie-Christine, Boyer, Jean-Christophe, Beroud, Christophe, Mbatchi, Litaty, van Kuilenburg, André, Bobin-Dubigeon, Christine, Thomas, Fabienne, Chatelut, Etienne, Merlin, Jean-Loui

Journal:

Year:

2017

Language:

english

File:

PDF, 1.94 MB

english, 2017

16

Optimized blood sampling with cytidine deaminase inhibitor for improved analysis of capecitabine metabolites

Thierry Besnard, Nicole Renée, Marie-Christine Etienne-Grimaldi, Eric François, Gérard Milano

Journal:

Journal of Chromatography B

Year:

2008

Language:

english

File:

PDF, 597 KB

english, 2008

17

Dissociation entre rôle pronostique et prédictif du récepteur de l’epidermal growth factor1 dans la réponse au géfitinib combiné à une radiochimiothérapie postopératoire ORL (essai CARISSA du Gortec 2004-02)

J. Thariat, R.-J. Bensadoun, M.-C. Etienne-Grimaldi, D. Grall, F. Penault-Llorca, O. Dassonville, P. Giraud, S. Racadot, E. Van Obberghen-Schilling, G. Milano

Journal:

Cancer/Radiothérapie

Year:

2012

Language:

french

File:

PDF, 65 KB

french, 2012

18

A Clinical Pharmacokinetic Analysis of Tegafur-Uracil (UFT) Plus Leucovorin Given in a New Twice-Daily Oral Administration Schedule

Marie-Christine Etienne-Grimaldi, Eric François, Jean-Michel Cardot, Nicole Renée, Jean-Yves Douillard, Erick Gamelin, Jaafar Bennouna, Yann Château, Dr Gérard Milano

Journal:

Clinical Pharmacokinetics

Year:

2007

Language:

english

File:

PDF, 139 KB

english, 2007

19

Traitements personnalisés grâce à la pharmacogénétique : niveaux de preuve et de recommandations du Réseau national de pharmacogénétique (RNPGx)

Picard, Nicolas, Boyer, Jean-Christophe, Etienne-Grimaldi, Marie-Christine, Barin-Le Guellec, Chantal, Thomas, Fabienne, Loriot, Marie-Anne

Journal:

Year:

2017

Language:

french

File:

PDF, 488 KB

french, 2017

20

Clinical relevance of MIR27A rs895819 polymorphism and its interaction with DPYD variants for predicting grade 4-5 fluoropyrimidine (FP) toxicity (tox) in the FUSAFE individual patient data meta-analysis (IPD-MA)

Etienne-Grimaldi, M-C., Cozic, N., Boige, V., Boyer, J-C., Meulendijks, D., Palles, C., Zanger, U., LargiadÃ¨r, C., Diasio, R.B., Jennings, B., Taieb, J., Deenen, M., Marinaki, T., Gross, E., van Kuil

Journal:

Annals of Oncology

Year:

2020

File:

PDF, 83 KB

2020

21

Pharmacogenetic profiling and cetuximab outcome in patients with advanced colorectal cancer

Laetitia Dahan, Emmanuelle Norguet, Marie-Christine Etienne-Grimaldi, Jean-Louis Formento, Mohamed Gasmi, Isabelle Nanni, Jean Gaudart, Stéphane Garcia, L’Houcine Ouafik, Jean-François Seitz, Gérard M

Journal:

Year:

2011

Language:

english

File:

PDF, 237 KB

english, 2011

22

Pharmacogénétique des fluoropyrimidines. La méthylènetétrahydrofolate réductase

M.-C. Etienne-Grimaldi, G. Milano

Journal:

Year:

2005

Language:

french

File:

PDF, 192 KB

french, 2005

23

Predicting the Response to EGFR Tyrosine Kinase Inhibitor Gefitinib in Head-and-Neck Cancer -- The Carissa GORTEC 2004-02 Study

Thariat, J., Bensadoun, R., Etienne-Grimaldi, M., Grall, D., Penault-Llorca, F., Dassonville, O., Cayre, A., Giraud, P., Van Obberghen-Schilling, E., Milano, G.

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2012

Language:

english

File:

PDF, 61 KB

english, 2012

24

Combination of sunitinib, cetuximab and irradiation in an orthotopic head and neck cancer model

Bozec, A., Sudaka, A., Toussan, N., Fischel, J.-L., Etienne-Grimaldi, M.-C., Milano, G.

Journal:

Annals of Oncology

Year:

2009

Language:

english

File:

PDF, 356 KB

english, 2009

25

PK/PD Model of Indisulam and Capecitabine: Interaction Causes Excessive Myelosuppression

Zandvliet, AS, Siegel-Lakhai, WS, Beijnen, JH, Copalu, W, Etienne-Grimaldi, M-C, Milano, G, Schellens, JHM, Huitema, ADR

Journal:

Clinical Pharmacology & Therapeutics

Year:

2007

Language:

english

File:

PDF, 762 KB

english, 2007

26

Vertical VEGF targeting: A combination of ligand blockade with receptor tyrosine kinase inhibition

Alexandre Bozec, François-Xavier Gros, Frédérique Penault-Llorca, Patricia Formento, Anne Cayre, Clélia Dental, Marie-Christine Etienne-Grimaldi, Jean-Louis Fischel, Gérard Milano

Journal:

European Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 914 KB

english, 2008

27

Frequent intragenic rearrangements of DPYD in colorectal tumours

van Kuilenburg, A B P, Etienne-Grimaldi, M-C, Mahamat, A, Meijer, J, Laurent-Puig, P, Olschwang, S, Gaub, M-P, Hennekam, R C M, Benchimol, D, Houry, S, Letoublon, C, Gilly, F-N, Pezet, D, Andre, T, Fa

Journal:

The Pharmacogenomics Journal

Year:

2015

Language:

english

File:

PDF, 1.03 MB

english, 2015

28

Lack of contribution of dihydrofluorouracil and ??-fluoro-??-alanine to the cytotoxicity of 5???-deoxy-5-fluorouridine on human keratinocytes

Fischel, Jean-Louis, Formento, Patricia, Ciccolini, Joseph, Etienne-Grimaldi, Marie-Christine, Milano, G.

Journal:

Anti-Cancer Drugs

Year:

2004

Language:

english

File:

PDF, 123 KB

english, 2004

29

Nuclear localization of a novel human syntaxin 1B isoform

Sandrine Pereira, Annick Massacrier, Patrice Roll, Alain Vérine, Marie-Christine Etienne-Grimaldi, Yannick Poitelon, Andrée Robaglia-Schlupp, Sarah Jamali, Nathalie Roeckel-Trevisiol, Barbara Royer, P

Journal:

Year:

2008

Language:

english

File:

PDF, 1.96 MB

english, 2008

30

K-Ras Mutations and Treatment Outcome in Colorectal Cancer Patients Receiving Exclusive Fluoropyrimidine Therapy

Etienne-Grimaldi, M.-C., Formento, J.-L., Francoual, M., Francois, E., Formento, P., Renee, N., Laurent-Puig, P., Chazal, M., Benchimol, D., Delpero, J.-R., Letoublon, C., Pezet, D., Seitz, J.-F., Mil

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 189 KB

english, 2008

31

Pharmacogénétique des récepteurs HER

G. Milano, M.-C. Etienne-Grimaldi, W. Lescaut

Journal:

Year:

2005

File:

PDF, 107 KB

2005

32

Antitumor activity of cetuximab associated with the taxotere–cisplatin–fluorouracil (TPF) combination on an orthotopic head and neck cancer model

Alexandre Bozec, Anne Sudaka, Marie-Christine Etienne-Grimaldi, Marie-Christine Brunstein, Jean-Louis Fischel, Gérard Milano

Journal:

Year:

2011

Language:

english

File:

PDF, 393 KB

english, 2011

33

ERCC1 and ERCC2 Polymorphisms Predict Clinical Outcomes of Oxaliplatin-Based Chemotherapies in Gastric and Colorectal Cancer: A Systemic Review and Meta-analysis

Yin, M., Yan, J., Martinez-Balibrea, E., Graziano, F., Lenz, H.-J., Kim, H.-J., Robert, J., Im, S.-A., Wang, W.-S., Etienne-Grimaldi, M.-C., Wei, Q.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 870 KB

english, 2011

34

Combination of mTOR and EGFR targeting in an orthotopic xenograft model of head and neck cancer

Bozec, Alexandre, Ebran, Nathalie, Radosevic-Robin, Nina, Sudaka, Anne, Monteverde, Martino, Toussan, Nicolas, Etienne-Grimaldi, Marie-Christine, Nigro, Cristiana Lo, Merlano, Marco, Penault-Llorca, F

Journal:

The Laryngoscope

Year:

2016

Language:

english

File:

PDF, 592 KB

english, 2016

35

Chronopharmacokinetics of Oral Tegafur and Uracil in Colorectal Cancer Patients

Etienne-Grimaldi, M-C, Cardot, J-M, François, E, Renée, N, Douillard, J-Y, Gamelin, E, Milano, G

Journal:

Clinical Pharmacology & Therapeutics

Year:

2007

Language:

english

File:

PDF, 121 KB

english, 2007

36

Pharmacokinetics of trabectedin on hemodialysis: an application for the management of cancer patients with end-stage renal disease

Juliette Thariat, Marie-Christine Etienne-Grimaldi, Vincent Launay-Vacher, Arturo Soto-Matos, Carlos Fernandez-Teruel, Thomas Ghafari, Pierre-Yves Marcy, Gérard Milano, Nicole Renée, Lauris Gastaud, A

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.64 MB

english, 2011

37

Combined effects of bevacizumab with erlotinib and irradiation: a preclinical study on a head and neck cancer orthotopic model

Bozec, A, Sudaka, A, Fischel, J-L, Brunstein, M-C, Etienne-Grimaldi, M-C, Milano, G

Journal:

British Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 236 KB

english, 2008

38

Influence of the VEGF-A 936C>T germinal polymorphism on tumoral VEGF expression in head and neck cancer

Formento, Jean-Louis, Etienne-Grimaldi, Marie-Christine, Francoual, Mireille, Pagès, Gilles, Onesto, Cercina, Formento, Patricia, Chamorey, Emmanuel, Dassonville, Olivier, Poissonnet, Gilles, Milano,

Journal:

Pharmacogenomics

Year:

2009

Language:

english

File:

PDF, 627 KB

english, 2009

39

Médicaments de haute technologie en oncologie

M. -C. Etienne-Grimaldi,P. Couvreur,J. -P. Benoit,R. Fanciullino…

Journal:

Year:

2014

Language:

french

File:

PDF, 407 KB

french, 2014

40

Pharmacokinetics of Irinotecan, Oxaliplatin and 5-Fluorouracil During Hepatic Artery Chronomodulated Infusion: A Translational European OPTILIV Study

Lévi, Francis, Karaboué, Abdoulaye, Etienne-Grimaldi, Marie-Christine, Paintaud, Gilles, Focan, Christian, Innominato, Pasquale, Bouchahda, Mohamed, Milano, Gérard, Chatelut, Etienne

Journal:

Clinical Pharmacokinetics

Year:

2017

Language:

english

File:

PDF, 1.27 MB

english, 2017

41

A Universal Formula Based on Cystatin C to Perform Individual Dosing of Carboplatin in Normal Weight, Underweight, and Obese Patients

Schmitt, A., Gladieff, L., Lansiaux, A., Bobin-Dubigeon, C., Etienne-Grimaldi, M.-C., Boisdron-Celle, M., Serre-Debauvais, F., Pinguet, F., Floquet, A., Billaud, E., Le Guellec, C., Penel, N., Campone

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 454 KB

english, 2009

42

Pharmacokinetics of sunitinib in hemodialysis

Izzedine, H., Etienne-Grimaldi, M. C., Renee, N., Vignot, S., Milano, G.

Journal:

Annals of Oncology

Year:

2008

Language:

english

File:

PDF, 47 KB

english, 2008

43

Pharmacogenetics of Capecitabine in Advanced Breast Cancer Patients

Largillier, R., Etienne-Grimaldi, M.-C., Formento, J.-L., Ciccolini, J., Nebbia, J.-F., Ginot, A., Francoual, M., Renee, N., Ferrero, J.-M., Foa, C., Namer, M., Lacarelle, B., Milano, G.

Journal:

Clinical Cancer Research

Year:

2006

Language:

english

File:

PDF, 310 KB

english, 2006

44

A routine feasible HPLC analysis for the anti-angiogenic tyrosine kinase inhibitor, sunitinib, and its main metabolite, SU12662, in plasma

Marie-Christine Etienne-Grimaldi, Nicole Renée, Hassan Izzedine, Gérard Milano

Journal:

Journal of Chromatography B

Year:

2009

Language:

english

File:

PDF, 183 KB

english, 2009

45

Combination of docetaxel and vandetanib in docetaxel-sensitive or resistant PC3 cell line

Monteverde, Martino, Tonissi, Federica, Fischel, Jean-Louis, Etienne-Grimaldi, Marie-Christine, Milano, Gerard, Merlano, Marco, Lo Nigro, Cristiana

Journal:

Urologic Oncology: Seminars and Original Investigations

Year:

2013

Language:

english

File:

PDF, 1.52 MB

english, 2013

46

Phase II Trial of Bevacizumab in Combination With Temozolomide as First-Line Treatment in Patients With Metastatic Uveal Melanoma

Piperno-Neumann, S., Diallo, A., Etienne-Grimaldi, M.-C., Bidard, F.-C., Rodrigues, M., Plancher, C., Mariani, P., Cassoux, N., Decaudin, D., Asselain, B., Servois, V.

Journal:

Year:

2016

Language:

english

File:

PDF, 542 KB

english, 2016

47

Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and FOLFOX response in colorectal cancer patients

Marie-Christine Etienne-Grimaldi, Gérard Milano, Frédérique Maindrault-Gœbel, Benoist Chibaudel, Jean-Louis Formento, Mireille Francoual, Gérard Lledo, Thierry André, May Mabro, Laurent Mineur, Michel

Journal:

British Journal of Clinical Pharmacology

Year:

2010

Language:

english

File:

PDF, 728 KB

english, 2010

48

Clinical value of circulating endothelial cells and circulating tumor cells in metastatic breast cancer patients treated first line with bevacizumab and chemotherapy

Bidard, F.- C., Mathiot, C., Degeorges, A., Etienne-Grimaldi, M.- C., Delva, R., Pivot, X., Veyret, C., Bergougnoux, L., de Cremoux, P., Milano, G., Pierga, J.- Y.

Journal:

Annals of Oncology

Year:

2010

Language:

english

File:

PDF, 125 KB

english, 2010

49

Methylenetetrahydrofolate reductase (MTHFR) variants and fluorouracil-based treatments in colorectal cancer

Etienne-Grimaldi, Marie-Christine, Francoual, Mireille, Formento, Jean-Louis, Milano, Gérard

Journal:

Pharmacogenomics

Year:

2007

Language:

english

File:

PDF, 180 KB

english, 2007

50

Gefitinib–trastuzumab combination on hormone-refractory prostate cancer xenograft

Patricia Formento, Jean-Michel Hannoun-Levi, Françoise Gérard, Christiane Mazeau, Jean-Louis Fischel, M.C. Etienne-Grimaldi, Jean Gugenheim, Gérard Milano

Journal:

European Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 167 KB

english, 2005

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